Statistics and Decision Analysis Platform

Florey Institute of Neuroscience and Mental Health


Dr. Leonid Churilov

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Post author: Leonid Churilov. Last update: 02/11/2015 at 10:11 am by Leonid Churilov.


Statistics and Decision Analysis academic platform provides expertise in the data, quantitative, and statistical aspects of basic science, clinical, imaging, and health services research carried out at Florey Institute of Neuroscience and Mental Health as well as Melbourne Brain Centre.

The primary goal of the academic platform is to support all the staff and postgraduate students with their research, as well as to assist external public bodies and private companies on a commercial basis. To achieve this goal, we focus our activities on the following three major interrelated themes:

  • Through collaboration with Melbourne Brain Centre researchers and our external clients, we provide expert assistance with research study design, analysis, and data management issues through all phases of a research study – from formulating a research plan and a study protocol to writing up the results;
  • We offer a range of training and development opportunities in the areas of study design, statistical analysis, and quantitative modelling
  • We conduct methodological research with the aim to provide tailored and rigorous quantitative methods to support evidence-based decision making in basic, clinical, and health services research.

The platform serves as a hub for collaboration within the Florey Institute of Neuroscience and Mental Health and with other Australian and international research institutions in the areas of statistical, data, and decision modelling. Within Melbourne Brain Centre we collaborate with basic science, clinical, and imaging neuroscience researchers. Academic platform’s external collaborators and clients include researchers and clinicians at Austin, Melbourne, Southern, Eastern, and Barwon Health Services and Royal Children’s Hospital  and  Murdoch Children’s Research Institute in Victoria; Hunter Medical Research Institute in New South Wales; Australian National Stroke Foundation;  Australasian Stroke Trials Network; as well as researchers from The University of Melbourne, RMIT University, Monash University, and University of Ballarat in Australia and various universities and research institutes across the globe, including USA, UK, Canada, Hong Kong, Japan, Norway, and Sweden.

We provide consulting services to health services policy makers at Victorian Department of Health and to a number of clinical research organizations, including Neuroscience Trials Australia – an Australian-based, not-for-profit contract research organisation specialising in clinical research.

To read more about our expertise, training and development opportunities, and the way we operate please click here for the Melbourne Brain Centre website.



We have specific expertise in design and analysis of animal experiments, all phases of human clinical trials, disease incidence studies, clinical registries, rehabilitation and allied health studies, inter- and intra-rater reliability studies, meta-analyses, studies with ordinal, survival, or count outcomes, imaging studies, and health services research studies including process of care models, systems modelling, optimization and simulation.
We collaborate on, and provide advice and consulting services regarding:

Statistical and design aspects of:

  • Protocol development
  • Ethics application development
  • External bodies funding application development
  • Presentations and writing up the results

Study design:

  • Refinement of research hypotheses and questions
  • Selection of appropriate outcome measures and measurement scales, stratification, and blocking mechanisms
  • Questionnaire design
  • Effect size elicitation from the literature through meta-analysis
  • Power analysis and sample size calculations
  • Creation of randomisation schedules

Statistical analysis:

  • Analysis planning
  • Statistical analysis
  • Programming of tables, listings and figures
  • Analysis services to Data Safety Monitoring Boards, including conducting interim analyses and statistical monitoring

Data management:

  • Specification and validation of data structures and data handling procedures
  • Design and maintenance of databases, electronic case report forms, and data entry screens
  • Validation/Consistency check programming
  • Development and Validation of Data Management Plans
  • Data capture and cleaning
  • Creating data sets from scanned forms

Statistics and Decision Analysis Platform

Florey Institute of Neuroscience and Mental Health, Melbourne Brain Centre (Heidelberg). Melbourne Brain Centre, 245 Burgundy St, Heidelberg, Victoria, Australia.

View location in Google maps. This location is based upon GPS coordinates as the street address does not accurately indicate the location of the facility.



Type: Core facility in a research organisation
Discipline areas: Mathematics
Precinct: Central, Northern
Affiliations: Florey Institute of Neuroscience and Mental Health

Tags: Data Management, eCRF, Power analysis and sample size calculations, Protocol development, Randomization Schedules, Statistical analysis