Mouse Cardiology Research Platform

Baker IDI Heart & Diabetes Institute

Contact

Dr. Xiao-Jun Du

(613) 8532 1267


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Post author: Xiao-Jun Du. Last update: 12/11/2015 at 11:44 am by Xiao-Jun Du.

Overview

Research conducted in this laboratory has centred on mechanisms and therapeutic intervention of cardiovascular remodeling, particularly inflammation, myocardial hypertrophy and fibrosis, as well as β-adrenergic signaling known to contribute to cardiac remodeling. We have been particularly interested in identifying factors that contribute to cardiac inflammation with consequent adverse remodeling after myocardial infarction.

Details

Benefits

Know how:Service 1:Producing heart disease models in mice

  • myocardial infarction
  • cardiac ischemia/reperfusion
  • aorta constriction (pressure overload)

Service 2: Gene/cell delivery by intra-myocardial injection

Service 3: Mouse electrocardiogram (ECG)

Service 4:Mouse transthoracic echocardiography, M-mode, 2-D loop, Doppler echocardiography.

Service 5:Mouse cardiac catheterization, baseline measure of blood pressure and cardiac function, drug administration and determining dose-response relation, pressure-volume catheterization.

Note: time-to-result depends on type of procedures, parameters to be analysed, duration of experiments and number of animals.

Expertise:Availability of technical support:

  • Technical support is available

Note that this material was imported form the Victorian Bioportal and content requires updating.

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Location

Mouse Cardiology Research Platform

Baker IDI Heart and Diabetes Institute. 75 Commercial Rd, Prahran, Victoria, Australia.

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Media

Categories


Type: Core facility in a research organisation
Discipline areas: Biological Science
Precinct: South east
Affiliations: Baker IDI Heart & Diabetes Institute

Biological Science categories: Animal models, Bioresources