Baker IDI Heart & Diabetes Institute
Post author: Xiao-Jun Du. Last update: 12/11/2015 at 11:44 am by Xiao-Jun Du.
Research conducted in this laboratory has centred on mechanisms and therapeutic intervention of cardiovascular remodeling, particularly inflammation, myocardial hypertrophy and fibrosis, as well as β-adrenergic signaling known to contribute to cardiac remodeling. We have been particularly interested in identifying factors that contribute to cardiac inflammation with consequent adverse remodeling after myocardial infarction.
Know how:Service 1:Producing heart disease models in mice
- myocardial infarction
- cardiac ischemia/reperfusion
- aorta constriction (pressure overload)
Service 2: Gene/cell delivery by intra-myocardial injection
Service 3: Mouse electrocardiogram (ECG)
Service 4:Mouse transthoracic echocardiography, M-mode, 2-D loop, Doppler echocardiography.
Service 5:Mouse cardiac catheterization, baseline measure of blood pressure and cardiac function, drug administration and determining dose-response relation, pressure-volume catheterization.
Note: time-to-result depends on type of procedures, parameters to be analysed, duration of experiments and number of animals.
Expertise:Availability of technical support:
- Technical support is available
Note that this material was imported form the Victorian Bioportal and content requires updating.