The Monash Immersive Visualisation Platform features CAVE2(TM) - a world-leading capability for the display and interactive exploration of rich and large datasets. It is used by scientists, engineers and artists to visualise, manipulate and comprehend data such as engineering models, multi-dimensional images across the size scale from nanoscopic to cosmic, and the outputs of scientific, computational and engineering simulations across the physical and life sciences and the arts and humanities.
X-Ray Crystallography supports structural biology and rational drug design
VLSCI is the biggest computation facility devoted to life sciences in the world, where researchers can access high-end compute resources and a range of experts to assist them - from research design through to data management and interpretation.
Virtual screening to facilitate structure-based drug design
Encompasses and uses the CSIRO Biomolecular Interaction Facility and the CSIRO Bio21 Crystallisation Centre to screen libraries of fragments as the first step towards rational drug design
The CSIRO Collaborative Crystallisation Centre (C3) is a full service protein crystallisation centre specialising in both screening and optimisation. C3 provides both expert and novice users access to technologies which will enable the rapid and efficient sampling of crystallisation space. Our core competency is high-throughput small volume (sub-microlitre) dispensing coupled with automatic imaging, but our strength lies in our ease of use, range of services and expert advice.
The CD spectromometer shines polarised light at proteins and allows analysis of protein secondary structure from circular dichroism spectra and aids monitoring of protein folding and conformational changes prior to using more expensive and time consuming methods such as NMR and X-ray crystallography
Nuclear Magnetic Resonance (NMR) spectroscopy determines the structures of molecules ranging from small chemicals to macromolecular proteins and nucleic acids. The NMR Facility contains eight NMR spectrometers available to academic and industry users on a fee for use basis. The massive 800 MHz high-field NMR spectrometer equipped with cyroprobe technology is signficant in its size and capability.
The Australian Synchrotron produces powerful beams of light that can be used to examine the atomic and molecular detail of a wide range of materials.