The VPTN provides a resource to local research community to present their research core facilities, instrumentation and services under a comprehensive website.
Encompasses and uses the CSIRO Biomolecular Interaction Facility and the CSIRO Bio21 Crystallisation Centre to screen libraries of fragments as the first step towards rational drug design
Bio Engineering is a broad-based branch of Engineering that is concerned with the design and construction of unit processes that harness biological systems to produce biotechnology products. Bio Engineering is at the interface of medicine, the life sciences, physics, mathematics, chemistry, and engineering. It employs an integrative approach to solving [...]
The HTCS Facility houses a Lead Discovery library currently containing ~200,000 compounds and robotics platforms to screen these small molecule chemical entities against biological targets of interest for drug discovery or for chemical biology outcomes. It has two core automation systems, the Hamilton MicroSTAR and PerkinElmer Minitrak IX systems as [...]
The Zetasizer Nano ZS (Malvern Instruments, UK) instrument uses light scattering techniques to determine the size distribution profile of particles in suspension. There is a well known correlation between the monodispersity of a protein sample and likely crystallisation success. It follows that trialing polydisperse samples in a crystallisation robot would [...]