The Synthetic Medicinal Chemistry group offers potential contract or collaborative research based on synthetic medicinal chemistry and other spectroscopic services.
This shared resource – incorporating the AAHL Biosecurity Microscopy Facility (ABMF) – provides world-class infrastructure and related technology platforms for researchers conducting projects requiring a high biocontainment/biosecure environment.
Nuclear Magnetic Resonance (NMR) spectroscopy determines the structures of molecules ranging from small chemicals to macromolecular proteins and nucleic acids. The NMR Facility contains eight NMR spectrometers available to academic and industry users on a fee for use basis. The massive 800 MHz high-field NMR spectrometer equipped with cyroprobe technology is signficant in its size and capability.
The HTCS Facility houses a Lead Discovery library currently containing ~200,000 compounds and robotics platforms to screen these small molecule chemical entities against biological targets of interest for drug discovery or for chemical biology outcomes. It has two core automation systems, the Hamilton MicroSTAR and PerkinElmer Minitrak IX systems as [...]
These laboratories contain state of the art medicinal chemistry research services. The laboratories are equipped with Bruker 300 MHz NMR with autosampler; Argonaut Flashmaster II; Waters Alliance Analytical HPLC with additional ELS detector; Finnigan LCQ Advantage Max LCMS; Mettler Toledo 12/24 Miniblock for multiple parallel synthesis and a CEM Microwave [...]