Custom designed targeting constructs, conditional knock-outs, knock-ins, reporter lines, point mutations, humanised genes, FLP deleter, CRE deleter transgenic constructs, BAC modifications for multiple organisms (mice, rat, human, primate, zebrafish, axolotl) southern screening strategies including cloning of southern probes. CRISPR technology, genotyping strategies, construct design.
The Medical Genomics Facility at the Monash Health Translation Precinct uses the latest and most innovative genomic technologies to service researchers throughout Australia. We maintain an excellent reputation for provision of the highest quality genomic data and client support.
The Australian Cancer Research Foundation (ACRF) Centre for Cancer Genomic Medicine is a newly established facility offering Next-Generation Sequencing. The centre will utilise the latest Life Technologies SOLiD 5500 and Ion Torrent systems in addition to complementary third generation sequencing systems.
A powerful technology for validating genome-wide association studies to orthogonally confirming NGS results. Can be used for genotyping and mutation detection and methylation anaylsis.
Melbourne Translational Genomics Platform makes genome analysis capabilities available to researchers of the University and precinct, accelerates adoption of these technologies in clinical practice, and supports research and clinical discovery. It is an evolving resource of cutting-edge technology and knowledge accessible to researchers and clinicians of all disciplines, and aims to foster cross-pollination of capabilities and experience between the University, clinical institutions and industry
X-ray diffraction provides a key methodology for determining the three dimensional structure of biological macromolecules to atomic or near atomic detail. However, before an X-ray diffraction experiment can be performed crystals of the molecule of interest are required. Efficient production of high-quality protein crystals for structure determination is one of major bottlenecks in Structural Biology. By improving the throughput and reproducibility of crystal production automation can improve the success rate of this process.
Micromon's DNA sequencing service is one of the key core facilities in Australia and has a nationwide reputation for its high quality data and reliable, customer-focused service. Micromon has an established high-throughput sequencing facility utilising Illumina Next-generation platform technology and this is coupled with access to a PC3/QC3 Quarantine bio-containment laboratory for imported biologicals.
The DNA & Blood Profiling Facility integrates proteomics, lipidomics, metabolomics, genomics and epigenomics so health problems can be examined from a multifaceted viewpoint
Australian Genome Research Facility Ltd (AGRF) is your local partner for genomic sequencing solutions. We are a not-for-profit company providing access to state-of-the-art facilities and expertise that enables genomic discovery in the scientific community. Our services cover Sequencing, Genotyping, Gene expression and DNA Extraction, all backed by our personalised advice and bioinformatics analysis.
The Victorian Centre for Functional Genomics at the Peter MacCallum Cancer Centre provides the infrastructure and expertise to perform small interfering (siRNA), micro RNA (miRNA), long non-coding RNA (lncRNA) and lentiviral-based short hairpin RNAi (shRNAmir) knockdown screens for functional genomics studies.