Used for Generation of transgenic animals by sperm mediated trasngenesis
Post author: Jose Gonzalez. Last update: 27/06/2014 at 2:24 pm by Jose Gonzalez.
ICSI-mediated transgenesis is a proven technique for the injection of large constructs such as BACs and YACs.
By ICSI injection using the Piezo Drill, large constructs are fully integrated into the rodent embryo’s genome.
The great advantage of this technique relies on the lack of fragmentation of the DNA construct injected.
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