Biostatistics

Service: Biostatistics

Used for high-quality and leading edge statistical methods to underpin research

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Post author: mcats. Last update: 25/02/2016 at 3:34 pm by mcats.

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Service overview

We provide high-quality biostatistical consulting and collaborative support to University of Melbourne researchers and our partners. We contribute to health science by developing, applying and promoting appropriate biostatistical methods including clinical trials, longitudinal cohort studies, and retrospective analyses of routinely collected data.

Engaging with a biostatistician at the beginning of a project and including them as one of the members of the investigative team, helps to ensure that the design, execution and interpretation of the research are of the highest quality. We would strongly recommend seeking biostatistical support to strengthen your research.

Additional info

CASE: A cluster randomised controlled trial, led by researchers at the Department of Medicine, The University of Melbourne:

Conducted in Vietnam to assess the effect of iron supplementation on maternal and infant outcomes (Hanieh S et al. PLoS Medicine 2013; NHMRC Project grant 628751). The clinical study investigators engaged with a biostatistician at the design stage of the study for advice regarding the choice of design (individual or cluster randomised trial), refinement of research questions, sample size calculation (in particular the pilot data required), random allocation of treatment groups (e.g. should this be stratified by any key confounders?) and proposed statistical analysis. Following initial consultations, the biostatistician became a key member of the investigator team and drafted sections of the successful NHMRC grant proposal, ethics application, study protocol, and statistical analysis plan. Following successful completion of the trial, another grant application was prepared, again with major involvement from the biostatistician (i.e. Chief Investigator), to follow-up the study’s cohort of infants to the age of three years in order to determine the critical pre- and post-natal influences on child growth and cognitive outcomes.
The second grant was successful in receiving $1,189,570 from the NHMRC (NHMRC Project grant APP1041988).

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Capacity: We encourage greater utilisation
Operation: Facility will train you, Facility provides the service for you
Access: Access by collaboration, Access by fee for service, Access by users external to managing organisation, Access by users internal to managing organisation