Leica GSD

Instrument: Leica GSD

Super Resolution Microscope used for Super resolution imaging


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Post author: Cameron Nowell. Last update: 20/01/2015 at 3:17 pm by Cameron Nowell.




Manufacturer: Leica, SR GSD 3D. Installed 2013.

Leica Ground State Depletion (GSD) microscope capable of single molecule super-resolution detection.

Funding sources: Institutional

Benefits of the Leica GSD

– Single molecule (20nm) resolution detection in up to 3 channels
– 3D (800nm in 50nm steps) capable
– Easy to use software
– TIRF mode available for super-resolution 2D imaging of cellular surfaces

Technical features and specifications

– 160x NA 1.47 TIRF objective
– 3 high powered laser lines (488nm, 561nm and 633nm)
– 405nm pump laser
– Fully adjustable TIRF depth from 80-400nm (fluorphore dependent)


Capacity: We encourage greater utilisation
Operation: User operated training provided, User or facility staff operate pricing may vary
Access: External researcher use available