Bio Atomic Force Microscope

Atomic Force Microscope used for Live cell imaging; Elastic properties of the cytoskeleton and cell adhesion; Single molecule studies on DNa, RNA, proteins, dendrimers, carbohydrates, lipids etc; Binding studies such as receptor/ligand or antibody/antigene; Intramolecular interactions protein folding, binding site localization etc; Biomaterial studies, biofouling, biosensors, capsules; Soft materials studies such as degration, mechanical or electrical properties; Polymer and thin film imaging and mapping; Nanoparticles, nanotubes, nanocomposites, vesicles, colloids, quantum dots; Electrochemistry from biomolecules to metal substrates.

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Post author: MCN. Last update: 26/09/2013 at 10:41 am by MCN.

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Overview

Manufacturer: JPK Instruments, NanoWizard || AFM. Installed 2010.

In-situ imaging in biological/chemical fluids or in air; Measurements at variable temperatures with perfusion possibilities; Large scan field of 100×100×15 µm3 with highest closed loop performance through capacitive sensors. The BioAFM equiped with a number of application modules such as Biocell (allows temperature dependent study of living cells or single molecues in their native environment), ECCell (for electrochemistry study from biomolecules to metal substrates), Kelvin Probe Module (for nanoscale mapping of surface potential distribution) and Heterodyne Thermal Noise Module (for determination of resonance frequencies up to 1MHz with the thermal noise method); sitted on an Accurion i4 active vibration isolation system (isolation performance: >5Hz = 25dB, 94.4% and >10Hz = 40dB, 99%); and housed in a JPK acoustic enclosure for utmost stability and isolation.

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Capacity: We encourage greater utilisation
Operation: User or facility staff operate pricing may vary