VLSCI is the biggest computation facility devoted to life sciences in the world, where researchers can access high-end compute resources and a range of experts to assist them - from research design through to data management.
Virtual screening to facilitate structure-based drug design
Expressions of Interest are now open for the Australasian Course in Macromolecular Crystallisation (ACMC 2013) The CSIRO Collaborative Crystallisation Centre (C3) is a full service protein crystallisation centre specialising in both screening and optimisation. C3 provides both expert and novice users access to technologies which will enable the rapid and efficient sampling of crystallisation space. Our core competency is high-throughput small volume (sub-microlitre) dispensing coupled with automatic imaging, but our strength lies in our ease of use, range of services and expert advice.
Encompasses and uses the CSIRO Biomolecular Interaction Facility and the CSIRO Bio21 Crystallisation Centre to screen libraries of fragments as the first step towards rational drug design
Nuclear Magnetic Resonance (NMR) spectroscopy determines the structures of molecules ranging from small chemicals to macromolecular proteins and nucleic acids. The NMR Facility contains eight NMR spectrometers available to academic and industry users on a fee for use basis. The massive 800 MHz high-field NMR spectrometer equipped with cyroprobe technology is signficant in its size and capability.
The Australian Synchrotron is a source of highly intense light…